{"id":7995,"date":"2023-05-31T06:26:58","date_gmt":"2023-05-31T06:26:58","guid":{"rendered":"https:\/\/medical.ezag.com\/?post_type=insight&p=7995"},"modified":"2026-01-22T11:44:07","modified_gmt":"2026-01-22T11:44:07","slug":"illuminating-innovation-q1-2023","status":"publish","type":"insight","link":"https:\/\/medical.ezag.com\/en\/insights\/illuminating-innovation-q1-2023\/","title":{"rendered":"Illuminating Innovation \u2013 Q1\/2023"},"content":{"rendered":"
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\n\t\t\t JUN<\/span>\n\t\t\t 20<\/span>\n\t\t\t <\/div>\n\t\t\t Nuclear Medicine<\/span>\n\t\t\t
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Illuminating Innovation \u2013 Q1\/2023<\/h1>\n\t\t\t

There is a lot of fascinating work being done out there that involves our products.

So we sat down and compiled a list for you with recent open access publications out there, where radionuclides or lab devices from Eckert & Ziegler have been used.

This is the start of a quarterly series. If you would like to see your publication in a future iteration, make sure to contact us!<\/p>\n\t\t\t <\/div>\n\t\t\t <\/div>Two people working with a Galliapharm\u00ae with EluGen<\/div>\n\t\t\t<\/section>\n\t\n\n

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Introduction to “Illuminating Innovation”<\/h2>\n
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For decades, we have been providing radionuclides<\/a>, radiopharmaceuticals<\/a>, radiosynthesizers<\/a> and QC equipment<\/a> to international institutions. There is now a long list of clinics and research institutes all over the world working with our products. And time and time again these institutions publish extraordinary work.<\/p>\n

To highlight their achievements, we compiled a list of publications from the first quarter of 2023, where one of our products was involved.<\/p>\n\n\n

Mostly open access articles<\/p>

Except for a select few publications, the list only includes open access articles. This is mainly due to the fact, that we can easily identify the involvement of our products in publications if access is not restricted. If you have published or are working on something with our products, make sure to contact us at marketing.medical@ezag.de<\/strong>, so we can add it or include it in a future edition, whether it be open access or not.<\/p>\n <\/div>\n\t\n\n\n

Enjoy reading through these interesting articles and see you next quarter!<\/p>\n\n\n\n\t\t

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Publications Q1 \/ 2023<\/h2>\n
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The publications are categorized by their field of medical application and sorted by their online publishing date (descending).<\/p>\n

CARDIOLOGY<\/strong><\/h3>\n

[68<\/sup>Ga]Ga-NODAGA-E[(cRGDyK)]2<\/sub> and [64<\/sup>Cu]Cu-DOTATATE PET Predict Improvement in Ischemic Cardiomyopathy<\/a><\/strong>
Jan 11, 2023 | Follin B et al.
Modular-Lab PharmTracer<\/a> and IGG100<\/a> used for the preparation of [68<\/sup>Ga]Ga-NODAGA-E[(cRGDyK)]2<\/sub><\/p>\n<\/p>\n

ENDOCRINOLOGY<\/strong><\/h3>\n

[18<\/sup>F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44<\/a><\/strong>
Feb 02, 2023 | Cheung P et al.
Flow-count<\/a> PMT detector used for semi-prep HPLC and radiochemical analysis of [18<\/sup>F]MK-7246<\/p>\n

Supramolecular nanofibers co-loaded with dabrafenib and doxorubicin for targeted and synergistic therapy of differentiated thyroid carcinoma<\/a><\/strong>
Jan 01, 2023 | Chen P et al.
Mini-Scan<\/a> used for radiochemical analysis of [125<\/sup>I]iodine-labeled supramolecular nanofibers<\/p>\n<\/p>\n

GASTROENTOROLOGY<\/strong><\/h3>\n

Radioimmune Imaging of \u03b14\u03b27 Integrin and TNF\u03b1 for Diagnostic and Therapeutic Applications in Inflammatory Bowel Disease<\/a><\/strong>
Mar 2, 2023 | Signore A et al.
Mini-Scan<\/span> used for radiochemical analysis of [99m<\/sup>Tc]technetium-labeled anti-TNF\u03b1 monoclonal antibodies<\/p>\n

68<\/sup>Ga-cyc-DX600 PET\/CT in ACE2-targeted tumor imaging<\/a><\/strong>
Feb 27, 2023 | Ren F et al.
Flow-count<\/a> used for radiochemical analysis of [68<\/sup>Ga]Ga-cyc-DX600<\/p>\n

Prospective Multicentric Assessment of 68<\/sup>Ga-DOTANOC PET\/CT in Grade 1-2 GEP-NET<\/a><\/strong>
Jan 14, 2023 | Lugat A et al.
Modular-Lab\u00a0PharmTracer<\/a> and GalliaPharm\u00ae<\/a> used for the preparation of [68<\/sup>Ga]Ga-DOTANOC<\/p>\n

Radiochemical Synthesis of 4-[18<\/sup>F]FluorobenzylAzide and Its Conjugation with EGFR-Specific Aptamers<\/a><\/strong>
Dec 30, 2022 | Il\u2018in VA et al.
Modular-Lab PharmTracer<\/a> used for the preparation of 4-[18<\/sup>F]fluorobenzylazide<\/p>\n<\/p>\n

HEMATOLOGY<\/strong><\/h3>\n

Automated synthesis and quality control of [68<\/sup>Ga]Ga-PentixaFor using the Gaia\/Luna Elysia-Raytest module for CXCR4 PET imaging<\/strong><\/a>
Feb 07, 2023 | Migliari S et al.
GalliaPharm\u00ae<\/a> and PentixaFor<\/a> precursor used for the preparation of [68<\/sup>Ga]Ga-PentixaFor<\/p>\n

PET\/CT of the Spleen with Gallium-Oxine-Labeled, Heat-Damaged Red Blood Cells: Clinical Experience and Technical Aspects<\/strong><\/a>
Feb 03, 2023 | Drescher R et al.
GalliaPharm\u00ae<\/span> used for the preparation of [68<\/sup>Ga]Ga-oxine<\/p>\n<\/p>\n

HEPATOLOGY<\/strong><\/h3>\n

Liver PET Reloaded: Automated Synthesis of [68<\/sup>Ga]Ga-BP-IDA for Positron Imaging of the Hepatobiliary Function and First Clinical Experience<\/strong><\/a>
Mar 16, 2023 | Werner A et al.
GalliaPharm\u00ae<\/a> used for the preparation of [68<\/sup>Ga]Ga-BP-IDA<\/p>\n<\/p>\n

NEUROLOGY<\/strong><\/h3>\n

Measurement of A\u03b2 Amyloid Plaques and Tau Protein in Postmortem Human Alzheimer\u2019s Disease Brain by Autoradiography Using [18<\/sup>F]Flotaza, [125<\/sup>I]IBETA, [124\/125<\/sup>I]IPPI and Immunohistochemistry Analysis Using QuPath<\/strong><\/a>
Mar 27, 2023 | Mondal R et al.
AR-2000<\/a> used for analysis of [18<\/sup>F]Flotaza, [125<\/sup>I]IBETA, [125<\/sup>I]IPPI<\/p>\n

Automated Synthesis of [18<\/sup>F]Flumazenil Application in GABAA Receptor Neuroimaging Availability for Rat Model of Anxiety<\/strong><\/a>
Mar 9, 2023 | Farn SS et al.
Flow-Count<\/span> used for radiochemical analysis of [18<\/sup>F]Flumazenil<\/p>\n

Abnormal [18<\/sup>F]NIFENE binding in transgenic 5xFAD mouse model of Alzheimer\u2019s disease: In vivo PET\/CT imaging studies of \u03b14\u03b22* nicotinic acetylcholinergic receptors and in vitro correlations with A\u03b2 plaques<\/strong><\/a>
Feb 23, 2023 | Liang C et al.
AR-2000<\/span> used for radiochemical analysis of [18<\/sup>F]flourine- and [125<\/sup>I]iodine-labeled compounds<\/p>\n

Synthesis and Biological Evaluation of Enantiomerically Pure (R)- and (S)-[18<\/sup>F]OF-NB1 for Imaging the GluN2B Subunit-Containing NMDA receptors<\/strong><\/a>
Jan 27, 2023 (preprint) | Korff M et al.
AR-2000<\/span> used for radiochemical analysis of [18<\/sup>F]flouride-labeled compounds<\/p>\n

Development of [124\/125<\/sup>I]IAZA as a New Proteinopathy Imaging Agent for Alzheimer\u2018s Disease<\/strong><\/a>
Jan 15, 2023 | Reddy TT et al.
AR-2000<\/span> used for radiochemical analysis of [124\/125<\/sup>I]IAZA<\/p>\n<\/p>\n

PNEUMOLOGY<\/strong><\/h3>\n

Safety, Biodistribution, and Dosimetry Study of Meplazumab, a Potential COVID-19 Therapeutic Drug, with 131<\/sup>I-Labeling and SPECT Imaging<\/strong><\/a>
Jan 20, 2023 | Ye J et al.
Mini-Scan<\/span> used for radiochemical analysis of [131<\/sup>I]iodine-labeled Meplazumab<\/p>\n<\/p>\n

UROLOGY<\/strong><\/h3>\n

Improved quality control of [177<\/sup>Lu]Lu-PSMA I&T<\/strong><\/a>
Mar 27, 2023 | Kraihammer M et al.
Modular-Lab PharmTracer<\/a> used for preparation of [177<\/sup>Lu]Lu-PSMA-I&T<\/p>\n

Selective ablation of TRA-1-60+ pluripotent stem cells suppresses tumor growth of prostate cancer<\/strong><\/a>
Mar 27, 2023 | White JM et al.
Mini-Scan<\/span> used for analysis of [89<\/sup>Zr]Zr-DFO-Bstrongomab and [177<\/sup>Lu]Lu-CHX-A\u201d-DTPA-Bstrongomab<\/p>\n

Comparison of Hormone-Sensitive Oligorecurrent Prostate Cancer Patients Based on Routine Use of Choline and\/or PSMA PET\/CT to Guide Metastasis-Directed Therapy<\/a><\/strong>
Mar 22, 2023 | Metz R et al.
Modular-Lab PharmTracer<\/span> used for preparation of [68<\/sup>Ga]Ga-PSMA-HBEDCC<\/p>\n

Multimodal Radiobioconjugates of Magnetic Nanoparticles Labeled with 44<\/sup>Sc and 47<\/sup>Sc for Theranostic Application<\/strong><\/a>
Mar 5, 2023 | \u00dcnak P et al.
AR-2000<\/a> used for radiochemical analysis of [44<\/sup>Sc]scandium- and [47<\/sup>Sc]scandium-labeled compounds<\/p>\n

Detection Efficacy of 68Ga-PSMA-11 PET\/CT in Biochemical Recurrence of Prostate Cancer with Very Low PSA Levels: A 7-Year, Two-Center \u201cReal-World\u201d Experience<\/a><\/strong>
Feb 21, 2023 | Burgard C et al.
GalliaPharm<\/a>\u00ae<\/span> used for the preparation of [68<\/sup>Ga]Ga-PSMA-11<\/p>\n

Baseline [68<\/sup>Ga]Ga-PSMA-11 PET\/CT before [177<\/sup>Lu]Lu-PSMA-617 Radioligand Therapy: Value of PSMA-Uptake Thresholds in Predicting Targetable Lesions<\/a><\/strong>
Jan 12, 2023 | Groener D et al.
GalliaPharm\u00ae<\/span> used for the preparation of [68<\/sup>Ga]Ga-PSMA-11<\/p>\n<\/p>\n

MULTIPLE APPLICATIONS<\/strong><\/h3>\n

SPECT Imaging with Tc-99m-Labeled HYNIC-FAPI-04 to Extend the Differential Time Window in Evaluating Tumor Fibrosis<\/a><\/strong>
Mar 10, 2023 | Luo X et al.
Mini-Scan<\/span> used for radiochemical analysis of [99m<\/sup>Tc]Tc-HYNIC-FAPI-04<\/p>\n

A novel molecular imaging probe [99m<\/sup>Tc]Tc-HYNIC-FAPI targeting cancer-associated fibroblasts<\/strong><\/a>
Mar 6, 2023 | Jinag Y et al.
Mini-Scan<\/span> used for radiochemical analysis of [99m<\/sup>Tc]Tc-HYNIC-FAPI<\/p>\n

Scandium-44 Radiolabeled Peptide and Peptidomimetic Conjugates Targeting Neuropilin-1 Co-Receptor as Potential Tools for Cancer Diagnosis and Anti-Angiogenic Therapy<\/strong><\/a>
Feb 15, 2023 | Maslowska K et al.
GalliaPharm\u00ae<\/a> used for the preparation of [68<\/sup>Ga]Ga-DOTA-Ahx-A7R and [68<\/sup>Ga]Lys(hArg)-Dab(Ahx-DOTA-Ga)-Pro-Arg<\/p>\n

Effects of Side Chain and Peptide Bond Modifications on the Targeting Properties of Stabilized Minigastrin Analogs<\/a><\/strong>
Feb 13, 2023 | Zavvar TS et al.
GalliaPharm\u00ae<\/span> used for radiolabeling of a variety of DOTA-compounds with [68<\/sup>Ga]gallium<\/p>\n

Towards Radiolabeled EGFR-Specific Peptides: Alternatives to GE11<\/strong><\/a>
Feb 11, 2023 | Judmann B et al.
GalliaPharm\u00ae<\/span> used for radiolabeling of a variety of compounds with [68<\/sup>Ga]gallium<\/p>\n

[99m<\/sup>Tc]Technetium-Labeled Niosomes: Radiolabeling, Quality Control, and In Vitro Evaluation<\/strong><\/a>
Feb 08, 2023 | Ekinci M et al.
AR-2000<\/a> used for radiochemical analysis of [99m<\/sup>Tc]technetium-labeled compounds<\/p>\n

In Vivo Evaluation of a Gallium-68-Labeled Tumor-Tracking Cyanine Dye for Positron Emission Tomography\/Near-Infrared Fluorescence Carcinoma Imaging, Image-Guided Surgery, and Photothermal Therapy<\/a><\/strong>
Feb 02, 2023 | Zhu J et al.
Flow-count<\/span> used for radiochemical analysis of [68<\/sup>Ga]Ga-DOTA-IR808<\/p>\n

Therapeutic Performance Evaluation of 213<\/sup>Bi-Labelled Aminopeptidase N (APN\/CD13)-Affine NGR-Motif ([213<\/sup>Bi]Bi-DOTAGA-cKNGRE) in Experimental Tumour Model: A Treasured Tailor for Oncology<\/a><\/strong>
Feb 01, 2023 | K\u00e9pes Z et al.
GalliaPharm\u00ae<\/span> used for the preparation of [68<\/sup>Ga]Ga-DOTAGA-cKNGRE<\/p>\n

Synthesis, Radiolabeling, and In Vitro and In Vivo Characterization of Heterobivalent Peptidic Agents for Bispecific EGFR and Integrin \u03b1v<\/sub>\u03b23 <\/sub>Targeting<\/a><\/strong>
Jan 04, 2023 | Braun D et al.
IGG100<\/a> used for preparation of [68<\/sup>Ga]NODAGA-PEG3<\/sub>-GE11-PEG3<\/sub>-c(RGDyK) and [68<\/sup>Ga]NODAGA-PEG5<\/sub>-GE11-PEG5<\/sub>-c(RGDfK)<\/p>\n<\/p>\n

OTHER<\/strong><\/h3>\n

\u201cClick-to-Clear\u201d: A Strategy to Minimize Radioactivity from the Blood Pool Utilizing Staudinger Ligation<\/a><\/strong>
Feb 21, 2023 | Soni N et al.
Flow-Count<\/span> used for radiodetection in [131<\/sup>I]iodine-labeled compounds<\/p>\n

Radiolysis-Associated Decrease in Radiochemical Purity of 177<\/sup>Lu-Radiopharmaceuticals and Comparison of the Effectiveness of Selected Quenchers against This Process<\/a><\/strong>
Feb 16, 2023 | Larenkov A et al.
MiniScanPRO<\/em><\/a> and Flow-count<\/span> used for radiochemical analysis of [177<\/sup>Lu]Lu-PSMA-617<\/p>\n

In Vitro Hemocompatibility and Genotoxicity Evaluation of Dual-Labeled [99m<\/sup>Tc]Tc-FITC-Silk Fibroin Nanoparticles for Biomedical Applications<\/a><\/strong>
Feb 07, 2023 | Asensio Ruiz MA et al.
AR-2000<\/a> used for radiochemical analysis of [99m<\/sup>Tc]Tc-FITC-SFN<\/p>\n

Peptide-based positron emission tomography probes: current strategies for synthesis and radiolabelling<\/strong><\/a>
Jan 06, 2023 | Failla M et al.
Modular-Lab PharmTracer<\/a> used for preparation of N-succinimidyl-4-[18<\/sup>F]fluorobenzoate<\/p>\n\n<\/section>\t\n\t\t\n\n

Want to see your publication here?<\/p>

If you would like to add your publication to one of the future iterations of \u201cIlluminating Innovation\u201d, make sure to contact us at marketing.medical@ezag.de<\/strong><\/p>\n <\/div>\n\t\n\n\t\t<\/div>\n\t \t

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\n Marius W\u00f6lfges\n
\n Marius W\u00f6lfges<\/span>\n Marketing Manager<\/span>\n <\/div>\n <\/div>\n
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This could be interesting for people in your network?<\/p>\n

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