Lutetium-177 Chloride Solution (n.c.a.)

Non-carrier-added Radiochemical for non-clinical research purposes

Non-carrier-added [177Lu]Lutetium Chloride solution for your research activities. The radiochemical solution is used for the preparation of radiolabeled compounds in the non-clinical research context.

Key Features

Lutetium-177 (n.c.a) is currently only available in non-GMP research grade. Our teams are working on the provision of GMP grade [177Lu]Lutetium Chloride solution starting in Q3 2022. Use the contact form at the end of the page to get in touch and find out more.

Detail Information

Lutetium-177 is a β-emitter with a half-life of 6.65 days. It can be produced via two different routes, direct by irradiation of Lutetium-176 for carrier-added or indirect by irradiation of Ytterbium-176 for non-carrier-added form. Lutetium-177 decays by emission of beta radiation (β: Emax= 498 keV) and gamma radiation (γ: 208 keV – 10.3 % abundance) to Hafnium-177.


Lutetium-177 has become more and more important over the last years as a substance used in many new radiopharmaceuticals, especially for cancer therapy. In combination with diagnostic [68Ga]-based-agents it is now the main therapeutic nuclide for theranostic approaches such as with DOTA-conjugated compounds for binding on the prostate specific membrane antigen (PSMA). A large number of further radiotherapeutic agents are currently under development for several types of cancer..

Method and specifications

Eckert & Ziegler offers Lutetium-177 in high quality no-carrier-added (n.c.a.) form. [177Lu]Lutetium Chloride Solution is produced by irradiation of [176Yb]Ytterbium and subsequent separation of [177Lu]Lutetium in our radiochemical facility. This process achieves highest purity.

Product [177Lu]Lutetium Chloride solution (clear and colorless)
Active Ingredient [177Lu]Lutetium Chloride, 40 GBq/mL
Excipients Hydrochloric Acid (0.04 M)
Chemical Form [177Lu]LuCl3 in 0.04 M hydrochloric acid solution
Activity as requested 4 – 200 GBq per vial* (activity tolerance ± 10%)
Radiochemical purity > 99.0 % [177Lu]Lutetium as Lu3+
Radionuclide purity

≥ 99,9%
[175Yb]Ytterbium ≤ 0.1%
[177mLu]Lutetium ≤ 0.07% 
All other radionuclide impurities ≤ 0.01%

pH 1 – 2
Sterility Sterile (from Q3 2022)

*traceable to PTB and NIST

Shipping and calibration

Eckert & Ziegler offers high flexibility regarding calibration time and date. A pre-calibration up to seven days is possible.
Lutetium-177 will be delivered within four business days worldwide.


Since March 2020, Eckert & Ziegler is supplying [177Lu]Lutetium Chloride solution to selected customers for non-clinical research. We are continuously expanding our production to provide additional batches to further customers. Furthermore, we plan to have Lutetium-177 in GMP quality available in 2022.

Timeline Lu-177

Product specific questions?

Eckert & Ziegler
Radiopharma GmbH
Robert-Rössle-Straße 10
13125 Berlin

+49 30 94 10 84 280
+49 30 94 10 84 470
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