About Eckert & Ziegler Medical

Who we are

EZ Medical is one of two business segments of the Eckert & Ziegler group. Decades of experience, a team of highly qualified employees and a strong network of international partners are what defines us and our work.

Our headquarters are located in Berlin, Germany.

Our Business Units

We are a reliable partner for you and your project. To this end we pooled multifaceted expertise from various areas to provide a comprehensive range of products and services in a wide field of activity:

Our Team

Although EZ Medical consists of multiple companies, we act in concert. Internal exchange of knowledge is the base of our daily operations and the key to our success. Our 330 colleagues cooperate to offer individual, valuable and innovative solutions. The highly qualified team comprises expertise in a multitude of areas. These professional skills combined with short communication paths make us cope with even the most complex challenges as a team.

Milestones

The beginnings of today’s company go back to the technical department of isotope production at the Nuclear Research Center in Dresden-Rossendorf.

Isotope Technologies Dresden GmbH

1964

1965

Isotope Technologies Dresden GmbH

Process development for the production of Mo-99 and I-131 on the basis of irradiated tellurium dioxide.

Invention of Ru-106 Eye Applicators

Eckert & Ziegler BEBIG GmbH

1969

Spin-off as Wälischmiller Dresden branch from the Central Institute for Nuclear Research.

Isotope Technologies Dresden GmbH

1991

1992

The beginning of Eckert & Ziegler, Berlin

Founding of BEBIG Isotopentechnik und Umweltdiagnostik GmbH (BEBIG GmbH), Berlin by Dr. Andreas Eckert and Jürgen Ziegler

A company that developed production lines, special sources and recycling processes for radioactive materials was arisen.

EUROTOPE Entwicklungsgesellschaft für Isotopentechnologien mbH, Berlin

1995

Founding of the holding company for a number of specialized subsidiaries.

Eckert & Ziegler Strahlen- und Medizintechnik AG, Berlin

1997

1999

Eckert & Ziegler BEBIG GmbH

Set up of the Seed production.

Registration of FDG-EZAG (Fludeoxyglucose (¹⁸F)).

FDG-EZAG

2000

Introduction of the first MultiSource^® afterloader.

Eckert & Ziegler BEBIG GmbH

2003

2005

Eckert & Ziegler Europe GmbH

Acquisition of 51% of the shares of f-con Europe GmbH.

Acquisition of 70% of EURO-PET Berlin Zyklotron GmbH, Berlin.

EURO-PET Berlin Zyklotron GmbH, Berlin

2005

POLATOM – complete hot cell complex for I-131 production.

Isotope Technologies Dresden GmbH

2005

2006

Yttriga

Registration of Yttriga ([⁹⁰Y]Yttrium chloride) in several European countries.

The beginning of our synthesis devices: with the Modular-Lab Standard.

Modular-Lab Standard

2006

Change of name to Isotope Technologies Dresden GmbH.

Isotope Technologies Dresden GmbH

2008

Isotope Technologies Dresden GmbH

Entry into the radiopharmaceuticals sector.

Acquisition of the isotope specialist Nuclitec GmbH, Braunschweig.

Eckert & Ziegler Nuclitec GmbH, Braunschweig

2009

The Modular-Lab PharmTracer is a cassette-based solution for routine production.

Modular-Lab PharmTracer

2009

2010

SonoTECH GmbH

Acquisition of SonoTECH GmbH. Development of brachytherapy treatment planning systems in-house starts.

King Faisal Specialist Hospital & Research Centre (Saudi Arabia) – Plant for the production of Tc-99m generators by aseptic loading.

Isotope Technologies Dresden GmbH

2010

BRIT (India) – Plant for the production of Tc99m generators by loading and subsequent autoclaving of the generator columns.

Isotope Technologies Dresden GmbH

2010

2011

Eckert & Ziegler Analytical Equipment

Acquisition of the Analytic Instrumentation and Radiochemistry Equipment Business from American market leader Bioscan, Inc.

Dimitrovgrad (Russia) – production of Mo-99 (from nuclear fission).

Isotope Technologies Dresden GmbH

2011

U.S. market entry and acquisition of Mick Radio-Nuclear Instruments, Inc.

Eckert & Ziegler BEBIG GmbH

2013

Modular-Lab eazy

The Modular-Lab eazy is the smallest automated synthesis system on the market.

Cern – Construction of the ISOLDE Alpha-Gamma Hot Cell for processing and disassembly of irradiated alpha-gamma targets.

Isotope Technologies Dresden GmbH

2013

Approval of the world’s first ⁶⁸Ge/⁶⁸Ga radionuclide generator for positron emission tomography (PET) in the diagnosis of cancer – the GalliaPharm^® .

GalliaPharm®

2014

Isotope Technologies Dresden GmbH

MURR (USA) – first plant in the USA – for the production ofI-131 based on irradiated tellurium dioxide.

Registration of GalliaPharm^® as a drug product in 12 countries of the European Union finalized.

GalliaPharm®

2015

FDA Inspection of GalliaPharm^® manufacturing facility in Berlin successfully passed.

GalliaPharm®

2015

2016

AAA’s NETSPOT®

AAA’s NETSPOT^® Gallium Ga 68 dotatate kit approval in the USA links GalliaPharm^® as the source of the ⁶⁸Ga.

European Commission has approved SomaKit TOC™ (AAA).

SomaKit TOC™

2016

HZDR (Germany) – PET hot cell line for synthesis, target handling/distribution and filling of PET radiopharmaceuticals.

Isotope Technologies Dresden GmbH

2016

2017

Eckert & Ziegler Radiopharma GmbH

Eckert & Ziegler Radiopharma sells its cyclotron division to Alliance Medical.

Launch of IsoSeed^® I25.S17plus for brain tumor treatment.

Eckert & Ziegler BEBIG GmbH

2017

Acquisition of WOLF-Medizintechnik GmbH (WOmed), a manufacturer of X-ray devices.

WOLF-Medizintechnik GmbH

2017

Isotope Technologies Dresden GmbH

Acquisition & rebranding by Eckert & Ziegler Strahlen- und Medizintechnik AG.

VTT (Finland) – Special facility built in close cooperation with VTT.

Isotope Technologies Dresden GmbH

2017

Launch of a shielded safety cabinet designed for the application of Tc-99m and Ga-68 and for ergonomic working.

Isotope Technologies Dresden GmbH

2018

KitLab

KitLab is a fully automated and user-friendly stand-alone device for safe processing of cold kits.

Chinese joint venture TCL Eckert & Ziegler BEBIG Healthcare (Wuxi) Co. Ltd. founded.

Eckert & Ziegler

2018

Construction of a production line for Lu-177 radiopharmaceuticals at the Eckert & Ziegler Radiopharma facility in Braunschweig, Germany.

Isotope Technologies Dresden GmbH

2018

2019

GalliaPharm®

Additional production capacities for GalliaPharm^® released by supervisory authorities.

Construction of a production line for Th-227 radiopharmaceuticals at the Eckert & Ziegler Radiopharma facility in Braunschweig, Germany.

Isotope Technologies Dresden GmbH

2019

Lutetium-177 starts its commercial production.

Lutetium-177

2020

Nuclear Medicine Europe

Eckert & Ziegler joins Nuclear Medicine Europe – the industry association.

Construction of a new production area with hot cells for active ingredient production.

Isotope Technologies Dresden GmbH

2020

Recovery of Ge-68/Ga-68 at the Eckert & Ziegler Radiopharma facility in Berlin.

Isotope Technologies Dresden GmbH

2020

2021

Eckert & Ziegler in Wilmington

A new cGMP facility for the contract manufacturing of radiopharmaceuticals and more in USA.

Extension of its cGMP production site in Berlin, Germany, with a new production facility.

Eckert & Ziegler Berlin

2021

Milestones

1964

2021

1964

Isotope Technologies Dresden GmbH

The beginnings of today’s company go back to the technical department of isotope production at the Nuclear Research Center in Dresden-Rossendorf.

1965

Isotope Technologies Dresden GmbH

Process development for the production of Mo-99 and I-131 on the basis of irradiated tellurium dioxide.

1969

Eckert & Ziegler BEBIG GmbH

Invention of Ru-106 Eye Applicators

1991

Isotope Technologies Dresden GmbH

Spin-off as Wälischmiller Dresden branch from the Central Institute for Nuclear Research.

1992

The beginning of Eckert & Ziegler, Berlin

Founding of BEBIG Isotopentechnik und Umweltdiagnostik GmbH (BEBIG GmbH), Berlin by Dr. Andreas Eckert and Jürgen Ziegler

1995

EUROTOPE Entwicklungsgesellschaft für Isotopentechnologien mbH, Berlin

A company that developed production lines, special sources and recycling processes for radioactive materials was arisen.

1997

Eckert & Ziegler Strahlen- und Medizintechnik AG, Berlin

Founding of the holding company for a number of specialized subsidiaries.

1999

Eckert & Ziegler BEBIG GmbH

Set up of the Seed production.

2000

FDG-EZAG

Registration of FDG-EZAG (Fludeoxyglucose (¹⁸F)).

2003

Eckert & Ziegler BEBIG GmbH

Introduction of the first MultiSource^® afterloader.

2005

Eckert & Ziegler Europe GmbH

Acquisition of 51% of the shares of f-con Europe GmbH.

2005

EURO-PET Berlin Zyklotron GmbH, Berlin

Acquisition of 70% of EURO-PET Berlin Zyklotron GmbH, Berlin.

2005

Isotope Technologies Dresden GmbH

POLATOM – complete hot cell complex for I-131 production.

2006

Yttriga

Registration of Yttriga ([⁹⁰Y]Yttrium chloride) in several European countries.

2006

Modular-Lab Standard

The beginning of our synthesis devices: with the Modular-Lab Standard.

2008

Isotope Technologies Dresden GmbH

Change of name to Isotope Technologies Dresden GmbH.

2008

Isotope Technologies Dresden GmbH

Entry into the radiopharmaceuticals sector.

2009

Eckert & Ziegler Nuclitec GmbH, Braunschweig

Acquisition of the isotope specialist Nuclitec GmbH, Braunschweig.

2009

Modular-Lab PharmTracer

The Modular-Lab PharmTracer is a cassette-based solution for routine production.

2010

SonoTECH GmbH

Acquisition of SonoTECH GmbH. Development of brachytherapy treatment planning systems in-house starts.

2010

Isotope Technologies Dresden GmbH

King Faisal Specialist Hospital & Research Centre (Saudi Arabia) – Plant for the production of Tc-99m generators by aseptic loading.

2010

Isotope Technologies Dresden GmbH

BRIT (India) – Plant for the production of Tc99m generators by loading and subsequent autoclaving of the generator columns.

2011

Eckert & Ziegler Analytical Equipment

Acquisition of the Analytic Instrumentation and Radiochemistry Equipment Business from American market leader Bioscan, Inc.

2011

Isotope Technologies Dresden GmbH

Dimitrovgrad (Russia) – production of Mo-99 (from nuclear fission).

2013

Eckert & Ziegler BEBIG GmbH

U.S. market entry and acquisition of Mick Radio-Nuclear Instruments, Inc.

2013

Modular-Lab eazy

The Modular-Lab eazy is the smallest automated synthesis system on the market.

2013

Isotope Technologies Dresden GmbH

Cern – Construction of the ISOLDE Alpha-Gamma Hot Cell for processing and disassembly of irradiated alpha-gamma targets.

2014

GalliaPharm®

Approval of the world’s first ⁶⁸Ge/⁶⁸Ga radionuclide generator for positron emission tomography (PET) in the diagnosis of cancer – the GalliaPharm^® .

2014

Isotope Technologies Dresden GmbH

MURR (USA) – first plant in the USA – for the production ofI-131 based on irradiated tellurium dioxide.

2015

GalliaPharm®

Registration of GalliaPharm^® as a drug product in 12 countries of the European Union finalized.

2015

GalliaPharm®

FDA Inspection of GalliaPharm^® manufacturing facility in Berlin successfully passed.

2016

AAA’s NETSPOT®

AAA’s NETSPOT^® Gallium Ga 68 dotatate kit approval in the USA links GalliaPharm^® as the source of the ⁶⁸Ga.

2016

SomaKit TOC™

European Commission has approved SomaKit TOC™ (AAA).

2016

Isotope Technologies Dresden GmbH

HZDR (Germany) – PET hot cell line for synthesis, target handling/distribution and filling of PET radiopharmaceuticals.

2017

Eckert & Ziegler Radiopharma GmbH

Eckert & Ziegler Radiopharma sells its cyclotron division to Alliance Medical.

2017

Eckert & Ziegler BEBIG GmbH

Launch of IsoSeed^® I25.S17plus for brain tumor treatment.

2017

WOLF-Medizintechnik GmbH

Acquisition of WOLF-Medizintechnik GmbH (WOmed), a manufacturer of X-ray devices.

2017

Isotope Technologies Dresden GmbH

Acquisition & rebranding by Eckert & Ziegler Strahlen- und Medizintechnik AG.

2017

Isotope Technologies Dresden GmbH

VTT (Finland) – Special facility built in close cooperation with VTT.

2018

Isotope Technologies Dresden GmbH

Launch of a shielded safety cabinet designed for the application of Tc-99m and Ga-68 and for ergonomic working.

2018

KitLab

KitLab is a fully automated and user-friendly stand-alone device for safe processing of cold kits.

2018

Eckert & Ziegler

Chinese joint venture TCL Eckert & Ziegler BEBIG Healthcare (Wuxi) Co. Ltd. founded.

2018

Isotope Technologies Dresden GmbH

Construction of a production line for Lu-177 radiopharmaceuticals at the Eckert & Ziegler Radiopharma facility in Braunschweig, Germany.

2019

GalliaPharm®

Additional production capacities for GalliaPharm^® released by supervisory authorities.

2019

Isotope Technologies Dresden GmbH

Construction of a production line for Th-227 radiopharmaceuticals at the Eckert & Ziegler Radiopharma facility in Braunschweig, Germany.

2020

Lutetium-177

Lutetium-177 starts its commercial production.

2020

Nuclear Medicine Europe

Eckert & Ziegler joins Nuclear Medicine Europe – the industry association.

2020

Isotope Technologies Dresden GmbH

Construction of a new production area with hot cells for active ingredient production.

2020

Isotope Technologies Dresden GmbH

Recovery of Ge-68/Ga-68 at the Eckert & Ziegler Radiopharma facility in Berlin.

2021

Eckert & Ziegler in Wilmington

A new cGMP facility for the contract manufacturing of radiopharmaceuticals and more in USA.

2021

Eckert & Ziegler Berlin

Extension of its cGMP production site in Berlin, Germany, with a new production facility.

Contact Us

Eckert & Ziegler Medical

medical@ezag.de

+49 30 94 10 84 0

+49 30 94 10 84 470

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