Automated 4-channel fluid transfer
Our Peristaltic Pump Module (PPM) type 54-3-0 is designed to avoid unnecessary radiation exposure and improve reproducibility when handling active and non active fluids. This is achieved by automating various fluid transfer tasks in the laboratory environment, especially during process optimization and R&D. The system enables the development of kit formulation processes while offering the possibility to transfer them to the KitLab system for use in routine production.
The daily work in radiochemistry and radiopharmaceutical laboratories requires several tasks involving active and non-active fluid transfers, such as production of tracers, dispensing, kit automation and more.
The Peristaltic Pump Module (PPM) type 54-3-0 is part of and compatible with the Modular-Lab technology and especially designed to fulfil various fluid transfer tasks in such laboratory environments. By automating these processes, reproducibility of results is improved and users can be protected from unnecessary radiation exposure in comparison to a fully manual handling, especially during optimization and development.
The PPM 54-3-0 uses a peristaltic pump with four independent channels to transfer fluids. The system is controlled with the well-established Modular-Lab software, which can be programmed by the operator according to the process requirements.
The tubing cassettes are fixed on the pump head by using purpose-built clasps and can be customized according to your needs. All basic cassette manifolds are designed for fail-free mounting and compatible with standard off-the-shelf components (filters, valves, etc.). This enables operators to develop own cassette designs and makes the PPM 54-3-0 an ideal module for in-house development. All data is stored in a comprehensive batch report.
The Peristaltic Pump Module can be used for any process involving fluid transfer, including the synthesis of radiotracers, dispensing and dilution as well as kit type labeling.
Automation of manual kit formulation processes
With the growing number of kits for the labeling of PET and other radiotracers, whether registered or still under development, the potential of manual handling errors and the risk of high radiation exposure to the operator increases. Approaches to minimize this potential by automation of the process have shown promising results.
With PPM 54-3-0 kit manufacturers are now offered the opportunity to automate their formulation in-house and develop their own specific processes according to the process guidelines or manuals.
Subsequently, Eckert & Ziegler offers the service to transfer these processes to the stand-alone device KitLab including the adaption of the software project to KitLab’s interface. Furthermore, the pre-designed tubing cassettes will be manufactured in Eckert & Ziegler’s production line under GMP-compliant clean room conditions to make them available in high quantities at a constant quality.
The KitLab process can be used by end customers as a simple standardized method in routine production in any laboratory afterwards.
Eckert & Ziegler offers basic tubing cassettes (sterile or non-sterile) using platinum cured silicone with an inner diameter of 1 mm.
Customized options (material, dimensions and accessories) provided upon request.